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Scientific reductionism leads pharmaceutical development into a crisis. Drugs, expected to work in the complex human body are being developed on single target cells. The human body is reduced to many simple, not well understood, systems using a reaction vessel. The hope is that these systems are able to mimic the human body – mostly an expensive error.
The developmental cycle of drugs, due to the historical pathway, is wasting resources, suboptimal and ineffective. New concepts like virtual screening and high throughput screening (HTS) make the situation even worse: The ineffective developmental cycle is now done even virtually and performed with huge inherent inefficiencies and bad performance. A logical way to develop a drug is substituted by human intuition and luck.
Instead of developing specific target systems and surrogate systems to mimic the human body we propose to see the development of a drug as a challenge to perfectly fit a molecule into the human body, which means that activity, metabolic stability, toxicity etc. do not exist as single entities, all criteria have to be seen as one criterion: "a good drug".
Therefore we use our artificial creativity systems to develop drugs in a way which is highly effective, superior to all existing technologies and guaranties success by using logical pathways instead of intuition and luck.
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